"DeNISTing" is a method to exclude (or partially parse) filetypes from indexation that are highly unlikely to contain evidentiary value. This will reduce the number of documents subject to review.
INDICA does this by setting up a database containing files and filetypes that highly unlikely to contain evidentiary value. During indexation, the found files are compared against the files in the database. Those with matching checksums are flagged as a 'deNIST' document and included in the index for the sake of completeness. The content, however, is not parsed.
During installation, INDICA offers to install and use deNIST. Installing this is optional.